The F-BAR protein family

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The DYRK-family kinase Pom1 phosphorylates the F-BAR protein Cdc15 to prevent division at cell poles

Division site positioning is critical for both symmetric and asymmetric cell divisions. In many organisms, positive and negative signals cooperate to position the contractile actin ring for cytokinesis. In rod-shaped fission yeast Schizosaccharomyces pombe cells, division at midcell is achieved through positive Mid1/anillin-dependent signaling emanating from the central nucleus and negative sig...

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Direct interaction of actin filaments with F-BAR protein pacsin2.

Two mechanisms have emerged as major regulators of membrane shape: BAR domain-containing proteins, which induce invaginations and protrusions, and nuclear promoting factors, which cause generation of branched actin filaments that exert mechanical forces on membranes. While a large body of information exists on interactions of BAR proteins with membranes and regulatory proteins of the cytoskelet...

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F-BAR proteins of the syndapin family shape the plasma membrane and are crucial for neuromorphogenesis.

Coordinated functions of the actin cytoskeleton and microtubules, which require careful control in time and space, are indispensable for the drastic alterations of neuronal morphology during neuromorphogenesis and neuronal network formation. Actin filament formation driven by the Arp2/3 complex and its activator neural Wiskott-Aldrich syndrome protein (N-WASP) is important for proper axon devel...

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Setting the Bar Too High F

I further like the boldness of Professor Lee’s strategy. The data presented by Justice Kennedy’s opinion for the Court in Roper v. Simmons would seem to be special in purporting to show a literally unanimous, worldwide rejection of the juvenile death penalty outside of the United States. 2 If even such a total worldwide consensus could be shown to lack instructiveness when applying the Eighth A...

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Targeting and functional mechanisms of the cytokinesis‑related F‑BAR protein Hof1 during the cell cycle

F-BAR proteins are membrane-associated proteins believed to link the plasma membrane to the actin cytoskeleton in cellular processes such as cytokinesis and endocytosis. In the budding yeast Saccharomyces cerevisiae, the F-BAR protein Hof1 localizes to the division site in a complex pattern during the cell cycle and plays an important role in cytokinesis. However, the mechanisms underlying its ...

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ژورنال

عنوان ژورنال: Communicative & Integrative Biology

سال: 2010

ISSN: 1942-0889

DOI: 10.4161/cib.3.2.10521